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Major achievements


1. Chromosome 1




2. Chromosome 2


We maintain neXtProt as the reference protein database for the C-HPP and provide yearly metrics to assess project advances
In collaboration with Chromosome 14 team, we have been looking for missing proteins from chromosome 2 in human sperm samples
We have highlighted a role for the unknown protein C2orf62 in ciliogenesis


C-HPP metrics

    • PMID 27487407(external link). Omenn GS, Lane L, Lundberg EK, Beavis RC, Overall CM, Deutsch EW. Metrics for the Human Proteome Project 2016: Progress on Identifying and Characterizing the Human Proteome, Including Post-Translational Modifications. J Proteome Res. 2016 Nov 4;15(11):3951-3960.
    • PMID 26155816(external link). Omenn GS, Lane L, Lundberg EK, Beavis RC, Nesvizhskii AI, Deutsch EW. Metrics for the Human Proteome Project 2015: Progress on the Human Proteome and Guidelines for High-Confidence Protein Identification. J Proteome Res. 2015 Sep 4;14(9):3452-60. doi: 10.1021/acs.jproteome.5b00499.
    • PMID 24364385 (external link). Lane L, Bairoch A, Beavis RC, Deutsch EW, Gaudet P, Lundberg E, Omenn GS. Metrics for the Human Proteome Project 2013-2014 and strategies for finding missing proteins. J Proteome Res. 2014 Jan 3;13(1):15-20. doi: 10.1021/pr401144x.

Standardization and guidelines

    • PMID:27490519(external link). Deutsch EW, Overall CM, Van Eyk JE, Baker MS, Paik YK, Weintraub ST, Lane L, Martens L, Vandenbrouck Y, Kusebauch U, Hancock WS, Hermjakob H, Aebersold R, Moritz RL, Omenn GS. Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1. J Proteome Res. 2016 Nov 4;15(11):3961-3970.
    • PMID:26367542(external link). Bruford EA, Lane L, Harrow J. Devising a Consensus Framework for Validation of Novel Human Coding Loci. J Proteome Res. 2015 Dec 4;14(12):4945-8. doi: 10.1021/acs.jproteome.5b00688.

neXtProt and associated tools

    • PMID 27899619 (external link). Gaudet P, Michel PA, Zahn-Zabal M, Britan A, Cusin I, Domagalski M, Duek PD, Gateau A, Gleizes A, Hinard V, Rech de Laval V, Lin J, Nikitin F, Schaeffer M, Teixeira D, Lane L, Bairoch A. Nucleic Acids Res. 2017 Jan 4;45(D1):D177-D182. doi: 10.1093/nar/gkw1062.
    • PMID 24364385 (external link). Gaudet P, Argoud-Puy G, Cusin I, Duek P, Evalet O, Gateau A, Gleizes A, Pereira M, Zahn-Zabal M, Zwahlen C, Bairoch A, Lane L. neXtProt: organizing protein knowledge in the context of human proteome projects. J Proteome Res. 2013 Jan 4;12(1):293-8. doi: 10.1021/pr300830v.
    • PMID 27173522 (external link). Sallou O, Duek PD, Darde TA, Collin O, Lane L, Chalmel F. PepPSy: a web server to prioritize gene products in experimental and biocuration workflows. Database (Oxford). 2016 May 12;2016. pii: baw070. doi: 10.1093/database/baw070.

Reviews

    • PMID 26680015 (external link). Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS. Systems Proteomics View of the Endogenous Human Claudin Protein Family. J Proteome Res. 2016 Feb 5;15(2):339-59. doi: 10.1021/acs.jproteome.5b00769. Review.

Identification of missing proteins

    • PMID 27444420(external link). Vandenbrouck Y, Lane L, Carapito C, Duek P, Rondel K, Bruley C, Macron C, Gonzalez de Peredo A, Couté Y, Chaoui K, Com E, Gateau A, Hesse AM, Marcellin M, Méar L, Mouton-Barbosa E, Robin T, Burlet-Schiltz O, Cianferani S, Ferro M,Fréour T, Lindskog C, Garin J, Pineau C. Looking for Missing Proteins in the Proteome of Human Spermatozoa: An Update. J Proteome Res. 2016 Nov 4;15(11):3998-4019.
    • PMID: 27487287(external link). Duek P, Bairoch A, Gateau A, Vandenbrouck Y, Lane L. Missing Protein Landscape of Human Chromosomes 2 and 14: Progress and Current Status. J Proteome Res. 2016 Nov 4;15(11):3971-3978. PubMed
    • PMID 26168773(external link). Jumeau F, Com E, Lane L, Duek P, Lagarrigue M, Lavigne R, Guillot L, Rondel K, Gateau A, Melaine N, Guével B, Sergeant N, Mitchell V, Pineau C. Human spermatozoa as a model for detecting missing proteins in the context of the chromosome-centric Human Proteome Project. J. Proteome Res. 2015 Sep 4;14(9):3621-34.
    • PMID 26132440(external link). Carapito C, Lane L, Benama M, Opsomer A, Mouton-Barbosa E, Garrigues L, Gonzalez de Peredo A, Burel A, Bruley C, Gateau A, Bouyssié D, Jaquinod M, Cianférani S, Burlet-Schiltz O, Van Dorsselaer A, Garin J, Vandenbrouck Y. Computational and mass spectrometry-based workflow for the discovery and validation of missing human proteins: application to chromosomes 2 and 14. J Proteome Res. 2015 Jul 1.

Functional characterization of chromosome 2 proteins

    • PMID 24475127(external link). Bontems F, Fish RJ, Borlat I, Lembo F, Chocu S, Chalmel F, Borg JP, Pineau C, Neerman-Arbez M, Bairoch A, Lane L. PLoS One. 2014 Jan 27;9(1):e86476. doi: 10.1371/journal.pone.0086476.



3. Chromosome 3




4. Chromosome 4




5. Chromosome 5


  • Setup Wiki for C-HPP (13 January 2013).
  • Poster at C-HPP poster session of HUPO 2013 (Yokohama, Japan): Chromosome-Centric Human Protein Project: Chromosome 5, Peter Horvatovich, Pei-Jing Pai, Henry Lam, Rainer Bischoff. Poster in pdf is available here.
  • Oral presentation at Young Investigator session and poster at HUPO 2013 (Yokohama, Japan): Pei-Jing Pai, Yingwei Hu, Henry Lam, Site-Specific N-Linked Glycosylation Analysis by Nano-LC Tandem Mass Spectrometry Coupled with a Spectral Library Searching Approach, References: YI03-03 11:29-11:41 for oral presentation and POS-03-016 for poster presentation.
  • Organizing a DTL focus meeting on "Data integration, standards and fair principles in proteomics" in Utrecht on August 29, 2016, Utrecht, The Netherlands. See program at DTL website(external link) and presentation on the C-HPP Wiki.
  • PhP test page



6. Chromosome 6


A review of the chromosome 6 project has been published, link(external link)
Borchers et al., 'The Human Proteome Organization Chromosome 6 Consortium: Integrating chromosome-centric and biology/disease driven strategies', Journal of Proteomics 100 (2014), 60-67.


7. Chromosome 7




8. Chromosome 8




9. Chromosome 9




10. Chromosome 10




11. Chromosome 11




12. Chromosome 12




13. Chromosome 13


  1. Set up home page for C-HPP (April 2012)
  2. Construct GenomewidePDB (December 2012)
  3. Update GenomewidePDB 2.0 (November 2015)
Publications
  • Paik,Y. et al. (2012) The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome. Nat Biotechnol, 30, 221-3. (PMID 22398612(external link))
  • Paik, Y. K. and Hancock, W. S. (2012) Uniting ENCODE with genome-wide proteomics. Nat. Biotechnol. 30, 1065-1067. (PMID 23138303)(external link))
  • Lee, H. J. et al. (2013) Comprehensive genome-wide proteomic analysis of human placental tissue for the Chromosome-Centric Human Proteome Project. J. Proteome Res., 12, 2458-2466. (PMID 23362793(external link))
  • Jeong, S. K. et al. (2013) GenomewidePDB, a proteomic database exploring the comprehensive protein parts list and transcriptome landscape in human chromosomes. J. Proteome Res., 12, 106-111. (PMID 23252913(external link))
  • Paik, Y. K. et al. (2014) Genome-wide proteomics, Chromosome-Centric Human Proteome Project (C-HPP), part II. J. Proteome Res., 13, 1-4. (PMID 24328071(external link))
  • Paik, Y. K. et al. (2015) Recent Advances in the Chromosome-Centric Human Proteome Project: Missing Proteins in the Spot Light. J. Proteome Res., 14, 3409-3414. (PMID 26337862(external link))
  • Jeong, S. K. et al. (2015) GenomewidePDB 2.0: A Newly Upgraded Versatile Proteogenomic Database for the Chromosome-Centric Human Proteome Project. J. Proteome Res., 14, 3710-3719. (PMID 26272709(external link))
  • Cho, J. Y. et al. (2015) Combination of Multiple Spectral Libraries Improves the Current Search Methods Used to Identify Missing Proteins in the Chromosome-Centric Human Proteome Project. J. Proteome Res., 14, 4959-4966. (PMID 26330117(external link))
  • Paik, Y. K. et al. (2016) Progress in the Chromosome-Centric Human Proteome Project as Highlighted in the Annual Special Issue IV. J. Proteome Res., 15, 3945-3950. (PMID 27809547(external link))
  • Kim, J. W. et al. (2016) gFinder: A Web-Based Bioinformatics Tool for the Analysis of N-Glycopeptides. J. Proteome Res., 15, 4116-4125. (PMID 27573070(external link))

14. Chromosome 14


  • Publications
    • PMID: 28891297(external link). Carapito C, Duek P, Macron C, Seffals M, Rondel K, Delalande F, Lindskog C, Freour T, Vandenbrouck Y, Lane L, Pineau C. Validating missing proteins in human sperm cells by targeted mass spectrometry- and antibody-based methods. J Proteome Res. 2017 Sep 11 doi: 10.1021/acs.jproteome.7b00374. Epub ahead of print
    • PMID 27444420(external link). Vandenbrouck Y, Lane L, Carapito C, Duek P, Rondel K, Bruley C, Macron C, Gonzalez de Peredo A, Couté Y, Chaoui K, Com E, Gateau A, Hesse AM, Marcellin M, Méar L, Mouton-Barbosa E, Robin T, Burlet-Schiltz O, Cianferani S, Ferro M,Fréour T, Lindskog C, Garin J, Pineau C. Looking for Missing Proteins in the Proteome of Human Spermatozoa: An Update. J Proteome Res. 2016 Nov 4;15(11):3998-4019.
    • PMID: 27487287(external link). Duek P, Bairoch A, Gateau A, Vandenbrouck Y, Lane L. Missing Protein Landscape of Human Chromosomes 2 and 14: Progress and Current Status. J Proteome Res. 2016 Nov 4;15(11):3971-3978. PubMed
    • PMID:27490519(external link). Deutsch EW, Overall CM, Van Eyk JE, Baker MS, Paik YK, Weintraub ST, Lane L, Martens L, Vandenbrouck Y, Kusebauch U, Hancock WS, Hermjakob H, Aebersold R, Moritz RL, Omenn GS. Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1. J Proteome Res. 2016 Nov 4;15(11):3961-3970.
    • PMID 26132440(external link). Carapito C, Lane L, Benama M, Opsomer A, Mouton-Barbosa E, Garrigues L, Gonzalez de Peredo A, Burel A, Bruley C, Gateau A, Bouyssié D, Jaquinod M, Cianférani S, Burlet-Schiltz O, Van Dorsselaer A, Garin J, Vandenbrouck Y. Computational and mass spectrometry-based workflow for the discovery and validation of missing human proteins: application to chromosomes 2 and 14. J Proteome Res. 2015 Jul 1.
    • PMID 26168773(external link). Jumeau F, Com E, Lane L, Duek P, Lagarrigue M, Lavigne R, Guillot L, Rondel K, Gateau A, Melaine N, Guével B, Sergeant N, Mitchell V, Pineau C. Human spermatozoa as a model for detecting missing proteins in the context of the chromosome-centric Human Proteome Project. J. Proteome Res. 2015 Sep 4;14(9):3621-34.
  • Posters and other media
    • Carapito C, Macron C, Duek P, Rondel K, Seffals M, Fréour T, Lindskog C, Vandenbrouck Y, Pineau C, Lane L. Taking up the “neXt50 challenge” using human sperm. 16th Human Proteome Organization World Congress, September 17-21, 2017, Dublin, Ireland. Poster
    • The French-Swiss Human Chromosome 2 and 14 consortium: Looking for missing proteins in the proteome of human spermatozoa. 15th Human Proteome Organization World Congress, September 18-22, 2016, Taipei, Taiwan. Oral communication
    • Vandenbrouck Y, Lane L, Pineau C, et al. The French-Swiss Human chromosome 2 and 14 consortium: looking for missing proteins in the proteome of human spermatozoa. 15th Human Proteome Organization (HUPO). Taipei, Taïwan. September 18-21th2016. Poster (C-HPP investigator award).
    • Pineau C. & Lane L. Call for a Testis/Epididymis proteome Project. 14th Human Proteome Organization (HUPO). Oral communication. Vancouver, Canada. September 27-30th 2015. Oral communication.
    • Vandenbrouck Y et al. Finding Missing Proteins in the Human Proteome. 10th Mass Spectrometry Applied to Proteomics (SMAP) congress. Ajaccio, France. September 15-18th 2015. Invited speaker.
    • Vandenbrouck Y et al. Computational and mass spectrometry-based workflow for the discovery and validation of missing proteins: the case of human chromosomes 2 and 14. 13th Human Proteome Organization (HUPO). Madrid, Spain. October 5-8th 2014. Oral communication.
    • Opsomer A, Benama M, Garrigues L, Lennon S, Mouton-Barbosa E, Van Dorsselaer A, Garin J, Vandenbrouck Y, Carapito C. Targeted proteomics experiments to validate so far “missing” human proteins. 10th Sienna Meeting. Italy, 31 August – 4 September 2014. Poster
    • Lane L, Bruley C, Christine Carapito C, Gateau A, Burel A, Gonzales de Peredo A, Bouyssié D, Schiltz-Burlet O, Monsarrat B, Van Dorsselaer A, Bairoch A, Garin J and Vandenbrouck Y. The Franco-Swiss c-HPP project: identifying missing proteins from chromosomes 2 and 14 using existing datasets and neXtProt annotations. HUPO 2013. Yokohama, Japan. 14-18th September 2013. Poster



15. Chromosome 15




16. Chromosome 16


Publications:
Posters presented in the HUPO 2013 (Yokohama, Japan) Meeeting:
Bioinformatic workflow for Chr16 characterization using proteomic shotgun and transcriptomic RNA-seq experiments
Development of SRM methods for the detection and quantification of chromosome 16 proteins
Dissecting subcellular compartments for deep proteome coverage of chromosome 16 in t cells
Improving Chr-16 proteins coverage with high confidence and MIAPE compliant MS data
Missing proteins in Chromosome 16 - Spanish HPP

Presentations:
Identification of proteins driving the progression of liver injury and potential biomarkers
How to submit MIAPE compliant data to ProteomeXchange Repository in the context of the human proteome project
Chromosome 16 Update: Surfing transcriptomics landscapes. A step beyond the annota=on of Chr-­‐16 proteome
European initiatives in the field of Proteomics Standarization

Other files:
SpanishContributiontoPX_Jan16.xlsx


17. Chromosome 17

We list here those.
proteins that were correlated with higher levels of EGFR or ERBB2 transcript, respectively.
EGFR signaling: caveolin 1 (CAV1), plectin (PLEC) (EGFR); growth factor receptor bound protein 7 (GRB7), Crk-like protein (CRKL) and Catenin delta-1 (CTNND1) (ERBB2).
Integrin signaling: filamin A (FLNA) and actinin alpha1 (ACTN1) (EGFR). MYC signaling: branched chain amino-acid transaminase 1 (BCAT1), carbamoyl-phosphate synthetase (CAD), nucleolin (NCL) (EGFR); transferrin receptor (TFRC), metadherin (MTDH) (ERBB2). p53 signaling: S100-A2 protein (S100A2), caveolin 1 (CAV1), Serpin B5 (SERPINB5), stratifin (SFN), PYD and CARD domain containing (PYCARD), and EPH receptor A2 (EPHA2) (EGFR).


18. Chromosome 18


  • Transcriptome profiling for chr18 in liver tissue and HepG2 cell line using RNA-Seq (Illumina and SOLiD) and RT-PCR protocols.
  • Proteome profiling for 276 master proteins coding on Chr18 in blood plasma, liver tissue and HepG2 cell line using SRM.
Image

Vienn diagram representing the number of chromosome 18 proteins detected by SRM in three types of biomaterial.
  • Construction Gene-Centric Knowledgebase(kb18) and SRM Registry (pikb18.ru) database for post-genomic data of Chr18.

Publications

  1. Alexander I. Archakov, Elena A. Ponomarenko, Ekaterina V. Poverennaya, Andrey V. Lisitsa, Ekaterina V. Ilgisonis, Mikhail A. Pyatnitskiy, Arthur T. Kopylov, Victor G. Zgoda. The size of the human proteome: the width and depth. 2014 (submitted).
  2. Lisitsa A, Moshkovskii S, Chernobrovkin A, Ponomarenko E, Archakov A. Profiling proteoforms: promising follow-up of proteomics for biomarker discovery. Expert Rev Proteomics. 2014 Feb;11(1):121-9. doi: 10.1586/14789450.2014.878652. PubMed PMID: 24437377.
  3. Ponomarenko EA, Kopylov AT, Lisitsa AV, Radko SP, Kiseleva YY, Kurbatov LK,Ptitsyn KG, Tikhonova OV, Moisa AA, Novikova SE, Poverennaya EV, Ilgisonis EV,Filimonov AD, Bogolubova NA, Averchuk VV, Karalkin PA, Vakhrushev IV, Yarygin KN,Moshkovskii SA, Zgoda VG, Sokolov AS, Mazur AM, Prokhortchouck EB, Skryabin KG,Ilina EN, Kostrjukova ES, Alexeev DG, Tyakht AV, Gorbachev AY, Govorun VM,Archakov AI. Chromosome 18 transcriptoproteome of liver tissue and HepG2 cells and targeted proteome mapping in depleted plasma: update 2013. J Proteome Res. 2014 Jan 3;13(1):183-90. doi: 10.1021/pr400883x. Epub 2013 Dec 13. PubMed PMID: 24328317.
  4. Shargunov AV, Krasnov GS, Ponomarenko EA, Lisitsa AV, Shurdov MA, Zverev VV, Archakov AI, Blinov VM. Tissue-specific alternative splicing analysis reveals the diversity of chromosome 18 transcriptome. J Proteome Res. 2014 Jan 3;13(1):173-82. doi: 10.1021/pr400808u. Epub 2013 Dec 9. PubMed PMID: 24320163.
  5. Poverennaya EV, Bogolubova NA, Bylko NN, Ponomarenko EA, Lisitsa AV, Archakov AI. Gene-centric content management system. Biochim Biophys Acta. 2014 Jan;1844(1 Pt A):77-81. doi: 10.1016/j.bbapap.2013.08.006. Epub 2013 Aug 27. PubMed PMID: 23994227.
  6. Ponomarenko E, Baranova A, Lisitsa A, Albar JP, Archakov A. The Chromosome-Centric Human Proteome Project at FEBS Congress. Proteomics. 2013 Nov 28. doi: 10.1002/pmic.201300373. Epub ahead of print PubMed PMID: 24285571.
  7. Naryzhny SN, Lisitsa AV, Zgoda VG, Ponomarenko EA, Archakov AI. 2DE-based approach for estimation of number of protein species in cell. Electrophoresis.2013 Nov 20. doi: 10.1002/elps.201300525. Epub ahead of print PubMed PMID:24259369.
  8. Kopylov AT, Zgoda VG, Lisitsa AV, Archakov AI. Combined use of irreversible binding and MRM technology for low- and ultralow copy-number protein detection and quantitation. Proteomics. 2013 Mar;13(5):727-42. doi: 10.1002/pmic.201100460. PubMed PMID: 23281252.
  9. Zgoda VG, Kopylov AT, Tikhonova OV, Moisa AA, Pyndyk NV, Farafonova TE, Novikova SE, Lisitsa AV, Ponomarenko EA, Poverennaya EV, Radko SP, Khmeleva SA, Kurbatov LK, Filimonov AD, Bogolyubova NA, Ilgisonis EV, Chernobrovkin AL, Ivanov AS, Medvedev AE, Mezentsev YV, Moshkovskii SA, Naryzhny SN, Ilina EN, Kostrjukova ES, Alexeev DG, Tyakht AV, Govorun VM, Archakov AI. Chromosome 18 transcriptome profiling and targeted proteome mapping in depleted plasma, liver tissue and HepG2 cells. J Proteome Res. 2013 Jan 4;12(1):123-34. doi: 10.1021/pr300821n. Epub 2012 Dec 20. PubMed PMID: 23256950.
  10. Archakov A, Zgoda V, Kopylov A, Naryzhny S, Chernobrovkin A, Ponomarenko E, Lisitsa A. Chromosome-centric approach to overcoming bottlenecks in the Human Proteome Project. Expert Rev Proteomics. 2012 Dec;9(6):667-76. doi: 10.1586/epr.12.54. Review. PubMed PMID: 23256676.
  11. Ponomarenko E, Poverennaya E, Pyatnitskiy M, Lisitsa A, Moshkovskii S, Ilgisonis E, Chernobrovkin A, Archakov A. Comparative ranking of human chromosomes based on post-genomic data. OMICS. 2012 Nov;16(11):604-11. doi: 10.1089/omi.2012.0034. Epub 2012 Sep 11. PubMed PMID: 22966780.
  12. Ershov P, Mezentsev Y, Gnedenko O, Mukha D, Yantsevich A, Britikov V, Kaluzhskiy L, Yablokov E, Molnar A, Ivanov A, Lisitsa A, Gilep A, Usanov S, Archakov A. Protein interactomics based on direct molecular fishing on paramagnetic particles: experimental simulation and SPR validation. Proteomics. 2012 Nov;12(22):3295-8. doi: 10.1002/pmic.201200135. Epub 2012 Nov 2. PubMed PMID: 23001861.
  13. Medvedev A, Kopylov A, Buneeva O, Zgoda V, Archakov A. Affinity-based proteomic profiling: problems and achievements. Proteomics. 2012 Feb;12(4-5):621-37. doi: 10.1002/pmic.201100373. Epub 2012 Jan 19. Review. PubMed PMID: 22246677.
  14. Archakov A, Aseev A, Bykov V, Grigoriev A, Govorun V, Ivanov V, Khlunov A, Lisitsa A, Mazurenko S, Makarov AA, Ponomarenko E, Sagdeev R, Skryabin K. Gene-centric view on the human proteome project: the example of the Russian roadmap for chromosome 18. Proteomics. 2011 May;11(10):1853-6. doi: 10.1002/pmic.201000540. PubMed PMID: 21563312.
  15. Archakov A, Ivanov Y, Lisitsa A, Zgoda V. Biospecific irreversible fishing coupled with atomic force microscopy for detection of extremely low-abundant proteins. Proteomics. 2009 Mar;9(5):1326-43. doi: 10.1002/pmic.200800598. PubMed PMID: 19253286.
  16. Archakov AI, Ivanov YD, Lisitsa AV, Zgoda VG. AFM fishing nanotechnology is the way to reverse the Avogadro number in proteomics. Proteomics. 2007 Jan;7(1):4-9. PubMed PMID: 17154275.


19. Chromosome 19


Chromosome 19 Team meeting, Salamanca, Spain, October 2-4, 2014


20. Chromosome 20


Publications in 2015
Publications in 2016



21. Chromosome 21




22. Chromosome 22




23. Chromosome X




24. Chromosome Y


2017
  • Meyfour A, Pooyan P, Pahlavan S, Rezaei-Tavirani M, Gourabi H, Baharvand H, Salekdeh GH. Chromosome-Centric Human Proteome Project Allies with Developmental Biology: a Case Study of the Role of Y chromosome Genes in Organ Development. J Proteome Res. 2017 Sep 15. doi: 10.1021/acs.jproteome.7b00446. PuMed PMID: 28914051(external link).
  • Meyfour A, Ansari H, Pahlavan S, Mirshahvaladi S, Rezaei-Tavirani M, Gourabi H, Baharvand H, Salekdeh GH. Y Chromosome Missing Protein, TBL1Y, May Play an Important Role in Cardiac Differentiation. J Proteome Res. 2017 Sep 13. doi: 10.1021/acs.jproteome.7b00391. PuMed PMID: 28853286(external link).

2015
  • Jangravi Z, Tabar MS, Mirzaei M, Parsamatin P, Vakilian H, Alikhani M, Shabani M, Haynes PA, Goodchild AK, Gourabi H, Baharvand H, Salekdeh GH. Two Splice Variants of Y Chromosome-Located Lysine-Specific Demethylase 5D Have Distinct Function in Prostate Cancer Cell Line (DU-145). J Proteome Res. 2015 Sep 4;14(9):3492-502. doi: 10.1021/acs.jproteome.5b00333. Epub 2015 Aug 10. PubMed PMID: 26215926(external link).
  • Ahmadi Rastegar D, Sharifi Tabar M, Alikhani M, Parsamatin P, Sahraneshin Samani F, Sabbaghian M, Sadighi Gilani MA, Mohammad Ahadi A, Mohseni Meybodi A, Piryaei A, Ansari-Pour N, Gourabi H, Baharvand H, Salekdeh GH. Isoform-Level Gene Expression Profiles of Human Y Chromosome Azoospermia Factor Genes and Their X Chromosome Paralogs in the Testicular Tissue of Non-Obstructive Azoospermia Patients. J Proteome Res. 2015 Sep 4;14(9):3595-605. doi: 10.1021/acs.jproteome.5b00520. PubMed PMID: 26162009(external link).
  • Vakilian H, Mirzaei M, Sharifi Tabar M, Pooyan P, Habibi Rezaee L, Parker L, Haynes PA, Gourabi H, Baharvand H, Salekdeh GH. DDX3Y, a Male-Specific Region of Y Chromosome Gene, May Modulate Neuronal Differentiation. J Proteome Res. 2015 Sep 4;14(9):3474-83. doi: 10.1021/acs.jproteome.5b00512. PubMed PMID: 26144214(external link).

2013
  • Jangravi Z, Alikhani M, Arefnezhad B, Sharifi Tabar M, Taleahmad S, Karamzadeh R, Jadaliha M, Mousavi SA, Ahmadi Rastegar D, Parsamatin P, Vakilian H, Mirshahvaladi S, Sabbaghian M, Mohseni Meybodi A, Mirzaei M, Shahhoseini M, Ebrahimi M, Piryaei A, Moosavi-Movahedi AA, Haynes PA, Goodchild AK, Nasr-Esfahani MH, Jabbari E, Baharvand H, Sedighi Gilani MA, Gourabi H, Salekdeh GH. A fresh look at the male-specific region of the human Y chromosome. J Proteome Res. 2013 Jan 4;12(1):6-22. doi: 10.1021/pr300864k. PubMed PMID: 23253012(external link).


25. Mitochondrial Chromosome